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Holding On to Hope

Nezelof's Syndrome
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Nezelof's Syndrome is an extremely rare immune deficiency disorder characterized by the impairment of cellular immunity against infections, especially by those agents that do not normally cause serious illness (opportunistic infections). In cell-mediated immune responses, specialized white blood cells known as T lymphocytes or "killer cells" help B lymphocytes respond to infectious foreign agents that invade the body. Nezelof's Syndrome may also include some abnormalities in humoral immunity. In this form of immune response, antibodies that are produced by specialized cells (i.e., B lymphocytes) circulate in the lymphatic fluid and blood. Antibodies fight off bacteria, viruses, and other foreign substances that threaten the body. B lymphocytes enable the body to produce and maintain circulating antibodies. In a subgroup of people with Nezelof's Syndrome, immune deficiency may be caused by a lack of the enzyme purine nucleoside phosphorylase (PNP).

Credit to -
www.rarediseases.org


Here are some charities you can donate to that will help with Nezelof's Syndrome:

American Academy of Allergy Asthma and Immunology
611 East Wells Street
Milwaukee, WI 53202
Phone #: 800-822-2762
E-mail: info@aaaai.org
Home page:
http://www.aaaai.org


Immune Deficiency Foundation
40 West Chesapeake Avenue
Towson, MD 21230
Phone #: 800-296-4433
E-mail: jb@primaryimmune.org
Home page:
http://www.primaryimmune.org


Here are some websites you can check out relating to Nezelof's Syndrome:


Never forget there is hope.